Question 1: Which 2 groups of rodents have two compartment stomachs?
Answer: murine rodents, and cricetine rodents...  murine rodents are in the family Muridae, subfamily Murinae, and include Old World rats and mice; cricetine rodents are in the family Muridae, subfamily Cricetinae, and include hamsters and white-tailed rats

Question 2: Can you name four rodent species that hibernate?
Answer: hamsters, white-tailed rats, some ground squirrels, and woodchucks

Question 3: Can you name six rodent species with, nonhipsodontic molars, or molars that do not extend very far, above the gum line?
Answer:  white footed mice, gerbils, cotton rats, white-tailed rats, squirrels, and woodchucks

Question 4: Can you name six rodent species that are susceptible to ringtail?
Answer: mice, white footed mice, rats, cotton rats, white-tailed rats, and woodchucks

Question 5: What is the coat color of A strain mice?
Answer: albino

Question 6: What is the accepted abbreviated strain symbol for AKR strain mice?
Answer: AK

Question 7: What is the coat color of AKR strain mice?
Answer: albino

Question 8: What is the accepted abbreviated strain symbol for BALB/c strain mice?
Answer: C

Question 9: What is the coat color of BALB/c strain mice?
Answer: albino 

Question 10: What is the coat color of SJL strain mice?
Answer: albino 

Question 11: What is the coat color of SWR strain mice?
Answer: albino 

Question 12: What is the accepted abbreviated strain symbol for C57BL strain mice?
Answer: B

Question 13: What is the coat color of C57BL strain mice?
Answer: black

Question 14: What is the accepted abbreviated strain symbol for C57BL/6 mice?
Answer: B6

Question 15: What is the coat color of C57BL/6 strain mice?
Answer: black

Question 16: What is the accepted abbreviated strain symbol for C57BL/10 mice?
Answer: B10

Question 17: What is the coat color of C57BL/10 strain mice?
Answer: black

Question 18: What is the accepted abbreviated strain symbol for CBA mice?
Answer: CB

Question 19: What is the coat color of CBA mice?
Answer: agouti

Question 20: What is the accepted abbreviated strain symbol for C3H mice?
Answer: C3

Question 21: What is the coat color of C3H strain mice?
Answer: agouti

Question 22: What is the accepted abbreviated strain symbol for C57BR/cd mice?
Answer: BR

Question 23: What is the coat color of C57BR/cd strain mice?
Answer: brown

Question 24: What is the accepted abbreviated strain symbol for DBA/1 mice?
Answer: D1

Question 25: What is the coat color of DBA/1 strain mice?
Answer: dilute brown non-agouti

Question 26: What is the accepted abbreviated strain symbol for DBA/2 mice?
Answer: D2

Question 27: What is the coat color of DBA/2 strain mice?
Answer: dilute brown non-agouti 

Question 28: What is the coat color of NH strain mice?
Answer: white, piebald, or tan

Question 29: What is the coat color of 129 strain mice?
Answer: agouti, albino, or chinchilla

Question 30: Can you name one strain of brown mice?
Answer: C57BR strain

Question 31: Can you name two strains of gray mice?
Answer: C57L strain, and DBA strain

Question 32: Can you name one strain of chinchilla and white mice?
Answer: 129/J

Question 33: Can you name the eight most commonly used inbred strains of rats?  (hint: inbred rats are Bee-Zee Workers For LABS)
Answer: BUF, the Buffalo rat; the Zucker rat; the Fisher 344 rat; WF, the Wistar Furth rat; LEW, the Lewis rat; ACI, the August Copenhagen Irish rat; BN, the Brown Norway rat; SHR, the spontaneously hypertensive rat

Question 34: Can you name the two major uses of the BUF rat, the Buffalo inbred rat strain?
Answer: the Buffalo inbred rat strain is a model for spontaneous autoimmune thyroiditis, and is a host for transplantable Morris hepatoma

Question 35: Can you name the two major uses of the Fisher 344 inbred rat strain?
Answer: the Fisher 344 rat is an inbred rat model for the National Toxicology Program's Carcinogen Bioassay Program, and for the National Institute on Aging

Question 36: Can you name the major use of the WF rat, the Wistar Furth inbred rat strain?
Answer: the Wistar Furth rat is a model for mononuclear cell leukemia

Question 37: Can you name the two major uses of the LEW rat, the Lewis inbred rat strain?
Answer: the Lewis rat is model for Multiple sclerosis, and is also a model for experimentally-induced autoimmune diseases

Question 38: Can you name the two major uses of the ACI, rat, the August Copenhagen Irish inbred rat strain?
Answer: the August Copenhagen Irish rat is a model for congenital genitourinary anomalies, and is also a model for prostatic adenocarcinoma

Question 39: Can you name the three major uses of the BN rat, the Brown Norway inbred rat strain?
Answer: the BN rat, the Brown Norway inbred rat is a model for inducible, transplantable myeloid leukemia, a model for hydronephrosis, and is a model for bladder carcinoma

Question 40: Can you name the two major uses of the SHR rat, the spontaneously hypertensive inbred rat strain?
Answer: the spontaneously hypertensive rat is a model of choice for studying hypertension, and is also a model of general use in cardiovascular research

Question 41: Can you name the four mutant rat strains most commonly used in research?
Answer: the Brattleboro rat, the Gunn rat, the Nude rat, and the Obese SHR rat

Question 42: Which mouse strains are resistant to Citrobacter infection?
Answer: DBA, NIH Swiss, C57BL

Question 43: Which mouse strain has increased susceptibility to Tyzzer's disease due to IgM deficiency?
Answer: XID mice

Question 44: Which mouse strains are susceptible to transmissible murine colonic hyperplasia, TMCH?
Answer: C3H/HeJ strain mice

Question 45: Which mouse strains are resistant to transmissible murine colonic hyperplasia, TMCH?
Answer: DBA mice, NIH Swiss mice, and C57BL mice

Question 46: Which mice are susceptible to hyperkeratosis caused by Corynebacterium bovis?
Answer: nude mice

Question 47: Which mouse strains are susceptible to Salmonella enteriditis, serovar typhimurium?
Answer: BALB/c mice, C57BL mice

Question 48: Which mouse strains are resistant to Salmonella enteriditis, serovar typhimurium?
Answer: A/J strain mice

Question 49: Which mouse strains are usually more susceptible to staphylococcus species?; (hint: remember the mnemonic, Staph "Can Cause A Bad Dermatitis")
Answer: C57BL/6 mice, C3H mice, A strain mice, BALB/c mice, and DBA strain mice

Question 50: Which mouse strains are usually more susceptible to murine leprosy?
Answer: C57BL/6 mice & BALB/c mice are more susceptible than DBA/2 mice

Question 51: Which mice are more susceptible to hepatitis with Helicobacter hepaticus?
Answer: BALB/c mice

Question 52: Which mice are more resistant to hepatitis with Helicobacter hepaticus?
Answer: C57BL/6 mice

Question 53: Which mouse strain develops the most severe hepatitis when infected with Helicobacter hepaticus?
Answer: aged, male, A/JCr mice.  This is noteworthy because it is common to see intestinal infections without liver pathology in Helicobacter hepaticus infections in mice

Question 54: Which mouse strains are susceptible to murine respiratory mycoplasmosis, or MRM?
Answer: C3H/HeN, mice, and  CBA/J mice

Question 55: Which mouse strains are resistant to murine respiratory mycoplasmosis, or MRM?
Answer: C57BL/6N mice.  (note: these are the NIH line of C57BL/6 mice)

Question 56: Which mouse strains are susceptible to ectromelia? (hint: remember the mnemonic: "A,B,C,D, ID")
Answer: A, BALB/c mice, C3H mice, DBA/1 mice, DBA/2 mice, and immune deficient mouse strains 

Question 57: Which mouse strains are resistant to ectromelia?
Answer: C57BL/6 mice, and AKR strain mice

Question 58: Which mouse strain has two distinct genes for respiratory resistance to ectromelia expressed via cell-mediated immunity, i.e., T-cells with cytotoxic activity and macrophages?
Answer: C57BL/6 mice

Question 59: What virus can cause polioencephalitis in old, immunosuppressed C58 mice?
Answer: lactate dehydrogenase elevating virus, or LDV

Question 60: Which mouse strain is the most susceptible to lactate dehydrogenase elevating virus, or LDV?
Answer: SJL/J strain mice

Question 61: Which mouse strains are susceptible to Sendai virus infection?
Answer: 129/ReJ mice, 129/J strain mice, DBA strain mice, nude mice, and immunosuppressed mice

Question 62: Which mouse strains are resistant to Sendai virus infection?
Answer: C57BL/6 mice, and outbred Swiss mice are highly resistant; RF/J strain mice, and SJL/J strain mice are moderately resistant

Question 63: Which mouse strains are highly susceptible to mouse hepatitis virus, or MHV?
Answer: nude mice, BALB/c mice, and PRI strain mice are highly susceptible to MHV, while DBA/2 strain mice are especially susceptible to the MHV-3  strain of mouse hepatitis virus

Question 64: Which mouse strains are moderately susceptible to mouse hepatitis virus, or MHV?
Answer: C3H/RV strain mice are moderately susceptible to MHV-3 

Question 65: Which mouse strains are resistant to mouse hepatitis virus, or MHV?
Answer: A strain mice, SJL strain mice, and A/J strain mice older than 3-4 weeks

Question 66: Which mouse strains are resistant to the MHV-2 strain of mouse hepatitis virus?
Answer: C3H/RV 

Question 67: Which mouse strains are resistant to the MHV-3  strain of mouse hepatitis virus?
Answer: A5 strain mice

Question 68: Which mouse strains are resistant to the JHM strain of mouse hepatitis virus, or MHV?
Answer: CD1 mice

Question 69: Which mouse strain has defective macrophages, which impairs wound repair?
Answer: P/J strain mice

Question 70: Which mouse strain is highly susceptible to severe, chronic demyelination from mouse encephalomyelitis virus, or MEV?
Answer: SJL/J

Question 71: Which mice are more susceptible to encephalomyocarditis virus (EMC)?
Answer: BALB/c, ICR strain, Swiss, SJL strain, and DBA/2

Question 72: Which mouse strain is more resistant to encephalomyocarditis virus?
Answer: C57BL

Question 73: Which mouse strains are more susceptible to Giardia?
Answer: C3H/He strain, DBA/2, and C57BL/6

Question 74: Which mouse strain is more resistant to Giardia?
Answer: BALB/c



Question 75: Which mouse strain develops exocrine pancreatic insufficiency?
Answer: CBA/J



Question 76: Which mouse strain is hairless, and is T-cell deficient?
Answer: athymic nudes

Question 77: Which mouse strain is an in vivo carrier of allogeneic and xenogeneic cells?
Answer: athymic nudes

Question 78: Which mouse strains have no T cells?
Answer: nude mice, and LASAT mice

Question 79: Which mouse strain has no B cells?
Answer: XID mice

Question 80: Which mouse strains have no B or T cells?
Answer: SCID mice, Rag-1, and Rag-2 mice

Question 81: Which mouse strain has no NK cells?
Answer: beige mice

Question 82: T- and B-cell deficient mouse strain that is highly susceptible to opportunistic agents such as Pneumocystis carinii?
Answer: SCID mice

Question 83: Which mouse strain has no T or NK cells?
Answer: motheaten mice

Question 84: Which mouse strains have no interferon?
Answer: pink mice, and cytokine knockout mice

Question 85:  In which mouse strain will ovariectomy dramatically reduce the incidence of mammary tumors?
Answer: C3H

Question 86: Which mouse strains develop chloroform toxicity?
Answer: female mice of strains A, CBA, C3H, and DBA

Question 87: Why is chloroform hepatic and renal toxic for females but not males of susceptible mouse strains?
Answer: the microsomes of females of susceptible strains metabolize chloroform 10 times slower than the microsomal metabolism in males

Question 88: Females of which mouse strain are resistant to the hepatic and renal toxic effects of chloroform?
Answer: C57BL/6 mice

Question 89: Can you name two black mouse strains that develop alopecia and/or  chronic ulcerative dermatitis?
Answer: C57BL/6, and C57BL/10 mice

Question 90: Which mouse strain is prone to develop, endocrine related, abdominal and thoracic, alopecia?
Answer: B6 C3 F1 hybrid mice



Question 91: Which mouse strain is especially aggressive, with fighting commonly noted among males?
Answer: BALB/c mice

Question 92: Which mouse strains are asplenic?
Answer: LASAT mice, and Dh/+, or dominant hemomelia, mice

Question 93: The nude mouse has no T-cells... what is the nude mouse's natural killer, or NK cell profile?
Answer: NK cells are increased in the nude mouse

Question 94: Which mouse strain is macrophage deficient and has poor reproduction?
Answer: P strain mice

Question 95: Which mouse strain is highly susceptible to infection with Mycoplasma avium-intracellulare?
Answer: C57BL/6N mice  (note: these are the NIH line of C57BL/6 mice)

Question 96: Which mouse strain commonly demonstrates pulmonary histiocytosis?
Answer: C57BL/6N mice  (note: these are the NIH line of C57BL/6 mice)

Question 97: Mallory Bodies are cytoplasmic inclusions made up of aggregates of intermediate filaments of prekeratin seen in ballooned, degenerating hepatocytes with hepatic disease or carcinomas.  Mallory bodies are considered a preneoplastic marker in which strain of mice?
Answer: C57BL/6 mice

Question 98: Which mouse strain has higher complement fixation antibodies than any other strain?
Answer: C57BL/6N mice  (note: these are the NIH line of C57BL/6 mice)

Question 99: Plasmacytomas are tumors used to produce monoclonal antibodies.  Which mouse strain is particularly well known for producing plasmacytomas when injected with mineral oil?
Answer: BALB/c mice

